By M. J. D'Amico
On November 23, 2013, the FDA announced that it had received approval for the sale of the drug Cialis® for use in men with erectile dysfunction (ED).
A study published in theJournal of the American Medical Associationon Tuesday found that men who had used Cialis had a 50% higher chance of having an erection at the time of their sexual activity. That is higher than the national average of 20% or more. The study was conducted with two different drugs.
In a separate study published in theon Monday, the researchers found that men who took the drugs had a 25% higher chance of having an erection at the time of their sexual activity.
A year ago, men who used Cialis, a prescription drug for erectile dysfunction, had an erection only if they were sexually aroused. But the researchers noted that Cialis may be associated with other side effects.
The FDA said that the approval was based on data from two large studies that involved over 5,000 men who were taking Cialis. The results showed that 36.8% of those who took the drugs had an erection after having sexual intercourse, compared to 11.1% of those who took the placebo. The average difference was -4.5 mm in the Cialis group and -3.2 mm in the placebo group.
The researchers said they believe the study provides important new information that could help physicians prescribe Cialis to their patients who have ED.
“The safety profile and effectiveness of Cialis have been well documented for many years and are considered safe for most men with ED,” said Dr. Andrew Wiles, M. D., an internist and researcher at New York’s Lenox Hill Hospital. “Cialis has been proven to be a safe and effective treatment for ED, and it is well tolerated by most men.”
The men taking the drugs in the study were given Cialis tablets to help relax erectile tissues and enhance blood flow to the penis, which helps men with ED achieve and maintain an erection.
Researchers noted that Cialis has been used to treat symptoms of erectile dysfunction. A study conducted in 1998 in the United States of America found that men taking Cialis, a phosphodiesterase-5 (PDE-5) inhibitor, had an 84% increased chance of having an erection when compared to men taking placebo. However, they also noted that the men taking Cialis had an increased likelihood of having an erection for less than six hours after taking the drug.
The men in the study were asked to report any side effects they had when they took Cialis. The men in the study were given an eight-day supply of the drug to help relax erectile tissue and improve blood flow to the penis. Cialis was then taken to treat a condition called penile shrinkage.
The men who took Cialis also were given a placebo or a dummy pill that they were given to treat ED for six months. In addition, Cialis was used to treat other conditions, including erectile dysfunction. The researchers also noted that Cialis has been shown to have an effect on sexual desire in over 90% of men taking the drugs. Cialis is sold under a number of brand names, including Viagra®, Cialis® and Levitra®.
The men who took the drugs had an increased likelihood of having an erection for less than six hours after taking the drug.
Dr. Wiles also noted that the study found that Cialis had a beneficial effect on erectile function among men with ED.
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Sildenafil citrateis used to treat erectile dysfunction (ED) in men. It is the generic version of Viagra and belongs to the class of drugs called PDE5 inhibitors. The drug has been shown to improve erections in patients with ED.
Dosage and AdministrationThe recommended dosage of Sildenafil citrate is one 50 mg tablet taken about 1 hour before sexual activity. The doctor will decide which tablet is most appropriate for you. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. It is important not to take more than one tablet in a 24-hour period.
InteractionsViagra may be taken with other medicines. Tell your doctor about all the medicines you are taking to avoid any interactions. The doctor may need to change the doses of your medicines.
Missed DoseIf you forget to take one tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not take a double dose.
StorageStore at room temperature, away from moisture and heat.
PrecautionsDo not use Sildenafil citrate if you have any of the following medical conditions: allergic disease, heart attack, irregular heartbeat, or sudden decrease or loss of vision in one or both eyes. Tell your doctor if you have kidney disease, liver disease, or any disease of the blood and muscle, or are taking any other medicines. This medication may not be safe for you to use. Keep this medicine out of reach of children.
P-ylene oxide (E171) - the main ingredient in ViagraE171 - the main ingredient in SildenafilP-ylene oxide (E171) - the main ingredient in SildenafilSildenafil citrate is a phosphodiesterase-5 (PDE-5) inhibitor. It works by helping to increase the blood flow in the penis, which helps to produce an erection. Sildenafil citrate is available as a generic medicine. You should not take this medicine if you are also taking nitrate-containing drugs. It is a drug that should not be used by men with chest pain, heart failure, or liver disease. It should not be used by men with a history of heart problems, high or low blood pressure, uncontrolled high or low magnesium levels, a history of stroke, heart attack, or unstable angina (chest pain) or severe heart failure. PDE5 inhibitors may also interfere with these PDE-5 enzymes. Sildenafil citrate can be taken with other PDE-5 inhibitors such as tadalafil and vardenafil. Tadalafil and vardenafil should not be taken together.
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Viagra (Sildenafil) is a prescription medication designed for men who are looking for an erectile dysfunction medication. It is used to treat conditions such as erectile dysfunction (ED) and premature ejaculation (PE). This means that men who have a condition that causes a decrease in sexual desire or difficulty in sexual intercourse should not take Viagra.
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If you experience any of these side effects or have any concerns, talk with your doctor or pharmacist.
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